Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ABCC6	HGNC:57 (HGNC) 368 (Entrez Gene) 603234 (OMIM) ABCC6 (Alliance of Genome Resources)	Chr16 p13.11	Chr16:16149565-16223522 (-) GRCh38	arterial calcification of infancy coronary artery disease pseudoxanthoma elasticum	O95255 (UniProt | EBI) NM_001079528 (RefSeq)
mouse	Abcc6	MGI:1351634 (MGI) 27421 (Entrez Gene) Gene Tree Abcc6 (Alliance of Genome Resources)	Chr7 29.64 cM	Chr7:45625804-45679915 (-) GRCm39	pseudoxanthoma elasticum	27421 (NCBI Gene Model) Q9R1S7 (UniProt | EBI) NM_018795 (RefSeq)
rat	Abcc6	RGD:620268 (Rat Genome Database) 81642 (Entrez Gene) Abcc6 (Alliance of Genome Resources)	Chr1 q22			O88269 (UniProt | EBI) NM_031013 (RefSeq)
zebrafish	abcc6a	ZDB-GENE-050517-18 (Zebrafish Model Organism Database) 566555 (Entrez Gene) abcc6a (Alliance of Genome Resources)	Chr6			XP_009300481 (RefSeq)
	abcc6b.1	ZDB-GENE-050517-19 (Zebrafish Model Organism Database) 100334180 (Entrez Gene) abcc6b.1 (Alliance of Genome Resources)	Chr3
	abcc6b.2	ZDB-GENE-110208-2 (Zebrafish Model Organism Database) 100002917 (Entrez Gene) abcc6b.2 (Alliance of Genome Resources)	Chr3			XP_017210293 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.