Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EPHB2	HGNC:3393 (HGNC) 2048 (Entrez Gene) 600997 (OMIM) EPHB2 (Alliance of Genome Resources)	Chr1 p36.12	Chr1:22710838-22921500 (+) GRCh38	blood platelet disease	P29323 (UniProt | EBI) NM_017449 (RefSeq)
mouse	Ephb2	MGI:99611 (MGI) 13844 (Entrez Gene) Gene Tree Ephb2 (Alliance of Genome Resources)	Chr4 69.0 cM	Chr4:136374850-136563299 (-) GRCm39		ENSMUSG00000028664 (Ensembl Gene Model) ENSMUSP00000058135 (Ensembl) ENSMUST00000059287 (Ensembl)
rat	Ephb2	RGD:1564232 (Rat Genome Database) 313633 (Entrez Gene) Ephb2 (Alliance of Genome Resources)	Chr5 q36			NP_001120791 (RefSeq) NM_001127319 (RefSeq)
zebrafish	ephb2a	ZDB-GENE-070713-2 (Zebrafish Model Organism Database) 562176 (Entrez Gene) ephb2a (Alliance of Genome Resources)	Chr23			XP_021325625 (RefSeq)
	ephb2b	ZDB-GENE-050522-415 (Zebrafish Model Organism Database) 554232 (Entrez Gene) ephb2b (Alliance of Genome Resources)	Chr11			NP_001314672 (RefSeq) NM_001033094 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.