Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CASP7	HGNC:1508 (HGNC) 840 (Entrez Gene) 601761 (OMIM) CASP7 (Alliance of Genome Resources)	Chr10 q25.3	Chr10:113679162-113730909 (+) GRCh38	Alzheimer's disease breast cancer colon cancer lung non-small cell carcinoma	P55210 (UniProt | EBI) NM_001267056 (RefSeq)
mouse	Casp7	MGI:109383 (MGI) 12369 (Entrez Gene) Gene Tree Casp7 (Alliance of Genome Resources)	Chr19 51.84 cM	Chr19:56385561-56430776 (+) GRCm39		ENSMUSG00000025076 (Ensembl Gene Model) ENSMUSP00000026062 (Ensembl) ENSMUST00000026062 (Ensembl)
rat	Casp7	RGD:620944 (Rat Genome Database) 64026 (Entrez Gene) Casp7 (Alliance of Genome Resources)	Chr1 q55			NP_071596 (RefSeq) NM_022260 (RefSeq)
zebrafish	casp7	ZDB-GENE-050522-506 (Zebrafish Model Organism Database) 553634 (Entrez Gene) casp7 (Alliance of Genome Resources)	Chr12			NP_001018443 (RefSeq) NM_001020607 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.