Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYL2	HGNC:7583 (HGNC) 4633 (Entrez Gene) 160781 (OMIM) MYL2 (Alliance of Genome Resources)	Chr12 q24.11	Chr12:110909996-111052434 (-) GRCh38	familial hypertrophic cardiomyopathy hypertrophic cardiomyopathy 10	P10916 (UniProt | EBI) NM_000432 (RefSeq)
mouse	Myl2	MGI:97272 (MGI) 17906 (Entrez Gene) Gene Tree Myl2 (Alliance of Genome Resources)	Chr5 Syntenic	Chr5:122239014-122251535 (+) GRCm39		ENSMUSG00000013936 (Ensembl Gene Model) ENSMUSP00000107379 (Ensembl) ENSMUST00000111750 (Ensembl)
rat	Myl2	RGD:1564245 (Rat Genome Database) 363925 (Entrez Gene) Myl2 (Alliance of Genome Resources)	Chr12 q16			P08733 (UniProt | EBI) NM_001035252 (RefSeq)
zebrafish	myl2a	ZDB-GENE-120917-2 (Zebrafish Model Organism Database) 100537244 (Entrez Gene) myl2a (Alliance of Genome Resources)	Chr5			NP_001373733 (RefSeq) NM_001386804 (RefSeq)
	myl2b	ZDB-GENE-060331-137 (Zebrafish Model Organism Database) 677750 (Entrez Gene) myl2b (Alliance of Genome Resources)	Chr8			NP_001035134 (RefSeq) NM_001040045 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.