Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SERPINI1	HGNC:8943 (HGNC) 5274 (Entrez Gene) 602445 (OMIM) SERPINI1 (Alliance of Genome Resources)	Chr3 q26.1	Chr3:167735243-167825569 (+) GRCh38	familial encephalopathy with neuroserpin inclusion bodies	Q99574 (UniProt | EBI) NM_001122752 (RefSeq)
mouse	Serpini1	MGI:1194506 (MGI) 20713 (Entrez Gene) Gene Tree Serpini1 (Alliance of Genome Resources)	Chr3 33.76 cM	Chr3:75464800-75549830 (+) GRCm39	familial encephalopathy with neuroserpin inclusion bodies	20713 (NCBI Gene Model) O35684 (UniProt | EBI) NM_009250 (RefSeq)
rat	Serpini1	RGD:619896 (Rat Genome Database) 116459 (Entrez Gene) Serpini1 (Alliance of Genome Resources)	Chr2 q32			Q9JLD2 (UniProt | EBI) NM_053779 (RefSeq)
zebrafish	serpini1	ZDB-GENE-060503-390 (Zebrafish Model Organism Database) 557627 (Entrez Gene) serpini1 (Alliance of Genome Resources)	Chr18			NP_001122164 (RefSeq) NM_001128692 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.