Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL12A	HGNC:5969 (HGNC) 3592 (Entrez Gene) 161560 (OMIM) IL12A (Alliance of Genome Resources)	Chr3 q25.33	Chr3:159988835-159996019 (+) GRCh38	hepatitis C hepatocellular carcinoma primary biliary cholangitis	P29459 (UniProt | EBI) NM_001354583 (RefSeq)
mouse	Il12a	MGI:96539 (MGI) 16159 (Entrez Gene) Gene Tree Il12a (Alliance of Genome Resources)	Chr3 31.92 cM	Chr3:68597977-68605880 (+) GRCm39		ENSMUSG00000027776 (Ensembl Gene Model) ENSMUSP00000029345 (Ensembl) ENSMUST00000029345 (Ensembl)
rat	Il12a	RGD:620562 (Rat Genome Database) 84405 (Entrez Gene) Il12a (Alliance of Genome Resources)	Chr2 q32			Q9R103 (UniProt | EBI) NM_053390 (RefSeq)
zebrafish	il12a	ZDB-GENE-060724-1 (Zebrafish Model Organism Database) 445410 (Entrez Gene) il12a (Alliance of Genome Resources)	Chr15			NP_001007108 (RefSeq) NM_001007107 (RefSeq)
	zmp:0000001127	ZDB-GENE-140106-87 (Zebrafish Model Organism Database) 100004358 (Entrez Gene) zmp:0000001127 (Alliance of Genome Resources)	Chr2			XP_017208075 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.