Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WDR4	HGNC:12756 (HGNC) 10785 (Entrez Gene) 605924 (OMIM) WDR4 (Alliance of Genome Resources)	Chr21 q22.3	Chr21:42843094-42892998 (-) GRCh38	Galloway-Mowat syndrome microcephaly, growth deficiency, seizures, and brain malformations	P57081 (UniProt | EBI) NM_033661 (RefSeq)
mouse	Wdr4	MGI:1889002 (MGI) 57773 (Entrez Gene) Gene Tree Wdr4 (Alliance of Genome Resources)	Chr17 16.56 cM	Chr17:31713296-31738946 (-) GRCm39		57773 (NCBI Gene Model) Q9EP82 (UniProt | EBI) NM_001405114 (RefSeq)
rat	Wdr4	RGD:1585179 (Rat Genome Database) 690032 (Entrez Gene) Wdr4 (Alliance of Genome Resources)	Chr20 p12			NP_001385973 (RefSeq) NM_001135667 (RefSeq)
zebrafish	wdr4	ZDB-GENE-060810-10 (Zebrafish Model Organism Database) 570351 (Entrez Gene) wdr4 (Alliance of Genome Resources)	Chr9			A4IGH4 (UniProt | EBI) NM_001126435 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.