Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADAM28	HGNC:206 (HGNC) 10863 (Entrez Gene) 606188 (OMIM) ADAM28 (Alliance of Genome Resources)	Chr8 p21.2	Chr8:24294069-24359014 (+) GRCh38	breast cancer estrogen-receptor positive breast cancer invasive ductal carcinoma lung adenocarcinoma lung non-small cell carcinoma	Q9UKQ2 (UniProt | EBI) NM_014265 (RefSeq)
mouse	Adam28	MGI:105988 (MGI) 13522 (Entrez Gene) Gene Tree Adam28 (Alliance of Genome Resources)	Chr14 35.69 cM	Chr14:68843476-68893291 (-) GRCm39		ENSMUSG00000014725 (Ensembl Gene Model) ENSMUSP00000022642 (Ensembl) ENSMUST00000022642 (Ensembl)
rat	Adam28	RGD:727820 (Rat Genome Database) 290344 (Entrez Gene) Adam28 (Alliance of Genome Resources)	Chr15 p11			NP_001381600 (RefSeq) NM_001394671 (RefSeq)
zebrafish	adam28	ZDB-GENE-060929-532 (Zebrafish Model Organism Database) 767749 (Entrez Gene) adam28 (Alliance of Genome Resources)	Chr5			NP_001070186 (RefSeq) NM_001076718 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.