Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FOXE3	HGNC:3808 (HGNC) 2301 (Entrez Gene) 601094 (OMIM) FOXE3 (Alliance of Genome Resources)	Chr1 p33	Chr1:47416285-47418052 (+) GRCh38	anterior segment dysgenesis anterior segment dysgenesis 2 cataract 34 multiple types thoracic aortic aneurysm	Q13461 (UniProt | EBI) NM_012186 (RefSeq)
mouse	Foxe3	MGI:1353569 (MGI) 30923 (Entrez Gene) Gene Tree Foxe3 (Alliance of Genome Resources)	Chr4 52.73 cM	Chr4:114782344-114783210 (-) GRCm39	congenital aphakia	ENSMUSG00000044518 (Ensembl Gene Model) ENSMUSP00000050445 (Ensembl) ENSMUST00000050940 (Ensembl)
rat	Foxe3	RGD:621727 (Rat Genome Database) 171302 (Entrez Gene) Foxe3 (Alliance of Genome Resources)	Chr5 q35			Q63250 (UniProt | EBI) NM_134339 (RefSeq)
zebrafish	foxe3	ZDB-GENE-061214-6 (Zebrafish Model Organism Database) 570855 (Entrez Gene) foxe3 (Alliance of Genome Resources)	Chr8			NP_001073150 (RefSeq) NM_001079682 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.