Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BTK	HGNC:1133 (HGNC) 695 (Entrez Gene) 300300 (OMIM) BTK (Alliance of Genome Resources)	ChrX q22.1	ChrX:101349338-101390796 (-) GRCh38	agammaglobulinemia B-cell lymphoma Burkitt lymphoma central nervous system lymphoma isolated growth hormone deficiency type III mantle cell lymphoma X-linked agammaglobulinemia	Q06187 (UniProt | EBI) NM_000061 (RefSeq)
mouse	Btk	MGI:88216 (MGI) 12229 (Entrez Gene) Gene Tree Btk (Alliance of Genome Resources)	ChrX 56.18 cM	ChrX:133443085-133484319 (-) GRCm39	X-linked agammaglobulinemia	ENSMUSG00000031264 (Ensembl Gene Model) ENSMUSP00000033617 (Ensembl) ENSMUST00000033617 (Ensembl)
rat	Btk	RGD:1359683 (Rat Genome Database) 367901 (Entrez Gene) Btk (Alliance of Genome Resources)	ChrX q32			NP_001007799 (RefSeq) NM_001007798 (RefSeq)
zebrafish	btk	ZDB-GENE-070531-1 (Zebrafish Model Organism Database) 568653 (Entrez Gene) btk (Alliance of Genome Resources)	Chr14			XP_697087 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.