Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DIO3	HGNC:2885 (HGNC) 1735 (Entrez Gene) 601038 (OMIM) DIO3 (Alliance of Genome Resources)	Chr14 q32.31	Chr14:101560139-101563452 (+) GRCh38		P55073 (UniProt | EBI) NM_001362 (RefSeq)
mouse	Dio3	MGI:1306782 (MGI) 107585 (Entrez Gene) Gene Tree Dio3 (Alliance of Genome Resources)	Chr12 60.56 cM	Chr12:110245664-110247531 (+) GRCm39		107585 (NCBI Gene Model) Q91ZI8 (UniProt | EBI) NM_172119 (RefSeq)
rat	Dio3	RGD:68420 (Rat Genome Database) 29475 (Entrez Gene) Dio3 (Alliance of Genome Resources)	Chr6			P49897 (UniProt | EBI) NM_017210 (RefSeq)
zebrafish	dio3a	ZDB-GENE-120406-7 (Zebrafish Model Organism Database) 100538339 (Entrez Gene) dio3a (Alliance of Genome Resources)	Chr17			NP_001242932 (RefSeq) NM_001256003 (RefSeq)
	dio3b	ZDB-GENE-070705-53 (Zebrafish Model Organism Database) 798872 (Entrez Gene) dio3b (Alliance of Genome Resources)	Chr20			NP_001171406 (RefSeq) NM_001177935 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.