Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	C8B	HGNC:1353 (HGNC) 732 (Entrez Gene) 120960 (OMIM) C8B (Alliance of Genome Resources)	Chr1 p32.2	Chr1:56929207-56974383 (-) GRCh38	type II complement component 8 deficiency	P07358 (UniProt | EBI) NM_001278544 (RefSeq)
mouse	C8b	MGI:88236 (MGI) 110382 (Entrez Gene) Gene Tree C8b (Alliance of Genome Resources)	Chr4 48.61 cM	Chr4:104623514-104661745 (+) GRCm39		110382 (NCBI Gene Model) Q8BH35 (UniProt | EBI) NM_133882 (RefSeq)
rat	C8b	RGD:2239 (Rat Genome Database) 313421 (Entrez Gene) C8b (Alliance of Genome Resources)	Chr5 q34			P55314 (UniProt | EBI) NM_001191759 (RefSeq)
zebrafish	c8b	ZDB-GENE-070912-163 (Zebrafish Model Organism Database) 793127 (Entrez Gene) c8b (Alliance of Genome Resources)	Chr2			NP_001243652 (RefSeq) NM_001256723 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.