Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DENND5A	HGNC:19344 (HGNC) 23258 (Entrez Gene) 617278 (OMIM) DENND5A (Alliance of Genome Resources)	Chr11 p15.4	Chr11:9138825-9265959 (-) GRCh38	developmental and epileptic encephalopathy 49	Q6IQ26 (UniProt | EBI) NM_001243254 (RefSeq)
mouse	Dennd5a	MGI:1201681 (MGI) 19347 (Entrez Gene) Gene Tree Dennd5a (Alliance of Genome Resources)	Chr7 57.62 cM	Chr7:109492987-109559677 (-) GRCm39		19347 (NCBI Gene Model) Q6PAL8 (UniProt | EBI) NM_021494 (RefSeq)
rat	Dennd5a	RGD:1306759 (Rat Genome Database) 308942 (Entrez Gene) Dennd5a (Alliance of Genome Resources)	Chr1 q33			G3V7Q0 (UniProt | EBI) NM_001107546 (RefSeq)
zebrafish	dennd5a	ZDB-GENE-071211-1 (Zebrafish Model Organism Database) 799847 (Entrez Gene) dennd5a (Alliance of Genome Resources)	Chr7			XP_001340162 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.