Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	APPL1	HGNC:24035 (HGNC) 26060 (Entrez Gene) 604299 (OMIM) APPL1 (Alliance of Genome Resources)	Chr3 p14.3	Chr3:57227726-57278105 (+) GRCh38	maturity-onset diabetes of the young type 14	Q9UKG1 (UniProt | EBI) NM_012096 (RefSeq)
mouse	Appl1	MGI:1920243 (MGI) 72993 (Entrez Gene) Gene Tree Appl1 (Alliance of Genome Resources)	Chr14 16.09 cM	Chr14:26640943-26692567 (-) GRCm39		72993 (NCBI Gene Model) Q8K3H0 (UniProt | EBI) NM_145221 (RefSeq)
rat	Appl1	RGD:1309388 (Rat Genome Database) 290537 (Entrez Gene) Appl1 (Alliance of Genome Resources)	Chr16 p16			NP_001386013 (RefSeq) NM_001399084 (RefSeq)
zebrafish	appl1	ZDB-GENE-081016-1 (Zebrafish Model Organism Database) 571540 (Entrez Gene) appl1 (Alliance of Genome Resources)	Chr11			NP_001121546 (RefSeq) NM_001128074 (RefSeq)
	hesx1	ZDB-GENE-990415-130 (Zebrafish Model Organism Database) 30620 (Entrez Gene) hesx1 (Alliance of Genome Resources)	Chr11			NP_571424 (RefSeq) NM_131349 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.