Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAPT	HGNC:6893 (HGNC) 4137 (Entrez Gene) 157140 (OMIM) MAPT (Alliance of Genome Resources)	Chr17 q21.31	Chr17:45894527-46028334 (+) GRCh38	Alzheimer's disease dementia frontotemporal dementia late onset Parkinson's disease Parkinson's disease Pick's disease progressive supranuclear palsy tauopathy temporal lobe epilepsy	P10636 (UniProt | EBI) NM_001377266 (RefSeq)
mouse	Mapt	MGI:97180 (MGI) 17762 (Entrez Gene) Gene Tree Mapt (Alliance of Genome Resources)	Chr11 67.79 cM	Chr11:104122216-104222916 (+) GRCm39		ENSMUSG00000018411 (Ensembl Gene Model) ENSMUSP00000102602 (Ensembl) ENSMUST00000106989 (Ensembl)
rat	Mapt	RGD:69329 (Rat Genome Database) 29477 (Entrez Gene) Mapt (Alliance of Genome Resources)	Chr10 q32.1			P19332 (UniProt | EBI) NM_017212 (RefSeq)
zebrafish	mapta	ZDB-GENE-081027-1 (Zebrafish Model Organism Database) 100000342 (Entrez Gene) mapta (Alliance of Genome Resources)	Chr12			XP_068080795 (RefSeq)
	maptb	ZDB-GENE-081027-2 (Zebrafish Model Organism Database) 567833 (Entrez Gene) maptb (Alliance of Genome Resources)	Chr3			XP_021329127 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.