Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PACS2	HGNC:23794 (HGNC) 23241 (Entrez Gene) 610423 (OMIM) PACS2 (Alliance of Genome Resources)	Chr14 q32.33	Chr14:105300563-105398147 (+) GRCh38	developmental and epileptic encephalopathy 66	Q86VP3 (UniProt | EBI) NM_015197 (RefSeq)
mouse	Pacs2	MGI:1924399 (MGI) 217893 (Entrez Gene) Gene Tree Pacs2 (Alliance of Genome Resources)	Chr12 61.57 cM	Chr12:112978128-113038021 (+) GRCm39		ENSMUSG00000021143 (Ensembl Gene Model) ENSMUSP00000152439 (Ensembl) ENSMUST00000223502 (Ensembl)
rat	Pacs2	RGD:1597262 (Rat Genome Database) 691631 (Entrez Gene) Pacs2 (Alliance of Genome Resources)	Chr6 q32			NP_001414258 (RefSeq) NM_001427329 (RefSeq)
zebrafish	pacs2	ZDB-GENE-081218-1 (Zebrafish Model Organism Database) 794778 (Entrez Gene) pacs2 (Alliance of Genome Resources)	Chr13			NP_001116223 (RefSeq) NM_001122751 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.