Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PROK2	HGNC:18455 (HGNC) 60675 (Entrez Gene) 607002 (OMIM) PROK2 (Alliance of Genome Resources)	Chr3 p13	Chr3:71771655-71785206 (-) GRCh38	hypogonadotropic hypogonadism 4 with or without anosmia	Q9HC23 (UniProt | EBI) NM_021935 (RefSeq)
mouse	Prok2	MGI:1354178 (MGI) 50501 (Entrez Gene) Gene Tree Prok2 (Alliance of Genome Resources)	Chr6 46.29 cM	Chr6:99688260-99703353 (-) GRCm39		ENSMUSG00000030069 (Ensembl Gene Model) ENSMUSP00000032152 (Ensembl) ENSMUST00000032152 (Ensembl)
rat	Prok2	RGD:620280 (Rat Genome Database) 192206 (Entrez Gene) Prok2 (Alliance of Genome Resources)	Chr4 q34			Q8R413 (UniProt | EBI) NM_138852 (RefSeq)
zebrafish	prok2	ZDB-GENE-100726-1 (Zebrafish Model Organism Database) 100006398 (Entrez Gene) prok2 (Alliance of Genome Resources)	Chr6			NP_001165870 (RefSeq) NM_001172399 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.