Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SETDB1	HGNC:10761 (HGNC) 9869 (Entrez Gene) 604396 (OMIM) SETDB1 (Alliance of Genome Resources)	Chr1 q21.3	Chr1:150926263-150964744 (+) GRCh38	autistic disorder lung cancer	Q15047 (UniProt | EBI) NM_001243491 (RefSeq)
mouse	Setdb1	MGI:1934229 (MGI) 84505 (Entrez Gene) Gene Tree Setdb1 (Alliance of Genome Resources)	Chr3 40.74 cM	Chr3:95230836-95264513 (-) GRCm39		84505 (NCBI Gene Model) O88974 (UniProt | EBI) NM_001163641 (RefSeq)
rat	Setdb1	RGD:1308370 (Rat Genome Database) 689883 (Entrez Gene) Setdb1 (Alliance of Genome Resources)	Chr2 q34			NP_001258104 (RefSeq) NM_001271175 (RefSeq)
zebrafish	setdb1b	ZDB-GENE-061013-224 (Zebrafish Model Organism Database) 768131 (Entrez Gene) setdb1b (Alliance of Genome Resources)	Chr16			Q08BR4 (UniProt | EBI) NM_001077277 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.