Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	THBD	HGNC:11784 (HGNC) 7056 (Entrez Gene) 188040 (OMIM) THBD (Alliance of Genome Resources)	Chr20 p11.21	Chr20:23045633-23049672 (-) GRCh38	acute kidney failure asthma atypical hemolytic-uremic syndrome carotid artery thrombosis cerebral infarction disseminated intravascular coagulation liver disease rheumatoid arthritis thrombophilia due to thrombomodulin defect	P07204 (UniProt | EBI) NM_000361 (RefSeq)
mouse	Thbd	MGI:98736 (MGI) 21824 (Entrez Gene) Gene Tree Thbd (Alliance of Genome Resources)	Chr2 73.45 cM	Chr2:148246391-148250108 (-) GRCm39	thrombophilia	21824 (NCBI Gene Model) P15306 (UniProt | EBI) NM_009378 (RefSeq)
rat	Thbd	RGD:621299 (Rat Genome Database) 83580 (Entrez Gene) Thbd (Alliance of Genome Resources)	Chr3 q41			NP_113959 (RefSeq) NM_031771 (RefSeq)
zebrafish	thbd	ZDB-GENE-110411-281 (Zebrafish Model Organism Database) 108180329 (Entrez Gene) thbd (Alliance of Genome Resources)	Chr20			XP_068071811 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.