Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WNK4	HGNC:14544 (HGNC) 65266 (Entrez Gene) 601844 (OMIM) WNK4 (Alliance of Genome Resources)	Chr17 q21.2	Chr17:42780610-42797066 (+) GRCh38	hypertension pseudohypoaldosteronism	Q96J92 (UniProt | EBI) NM_001321299 (RefSeq)
mouse	Wnk4	MGI:1917097 (MGI) 69847 (Entrez Gene) Gene Tree Wnk4 (Alliance of Genome Resources)	Chr11 64.51 cM	Chr11:101151393-101168235 (+) GRCm39	Gitelman syndrome pseudohypoaldosteronism	ENSMUSG00000035112 (Ensembl Gene Model) ENSMUSP00000099397 (Ensembl) ENSMUST00000103108 (Ensembl)
rat	Wnk4	RGD:631401 (Rat Genome Database) 287715 (Entrez Gene) Wnk4 (Alliance of Genome Resources)	Chr10 q31			Q7TPK6 (UniProt | EBI) NM_175579 (RefSeq)
zebrafish	wnk4a	ZDB-GENE-110606-2 (Zebrafish Model Organism Database) 100330953 (Entrez Gene) wnk4a (Alliance of Genome Resources)	Chr12			XP_002663933 (RefSeq)
	wnk4b	ZDB-GENE-131120-119 (Zebrafish Model Organism Database) 557091 (Entrez Gene) wnk4b (Alliance of Genome Resources)	Chr3			XP_685164 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.