Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPRED2	HGNC:17722 (HGNC) 200734 (Entrez Gene) 609292 (OMIM) SPRED2 (Alliance of Genome Resources)	Chr2 p14	Chr2:65307175-65432637 (-) GRCh38	Noonan syndrome	Q7Z698 (UniProt | EBI) NM_181784 (RefSeq)
mouse	Spred2	MGI:2150019 (MGI) 114716 (Entrez Gene) Gene Tree Spred2 (Alliance of Genome Resources)	Chr11 12.79 cM	Chr11:19874442-19974026 (+) GRCm39	achondroplasia	114716 (NCBI Gene Model) Q924S7 (UniProt | EBI) NM_033523 (RefSeq)
rat	Spred2	RGD:1309304 (Rat Genome Database) 305539 (Entrez Gene) Spred2 (Alliance of Genome Resources)	Chr14 q22			Q3C2P8 (UniProt | EBI) NM_001047094 (RefSeq)
zebrafish	spred2a	ZDB-GENE-110830-2 (Zebrafish Model Organism Database) 558432 (Entrez Gene) spred2a (Alliance of Genome Resources)	Chr1			XP_686737 (RefSeq)
	spred2b	ZDB-GENE-040426-2342 (Zebrafish Model Organism Database) 793290 (Entrez Gene) spred2b (Alliance of Genome Resources)	Chr13			Q6NYK3 (UniProt | EBI) NM_213234 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.