Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SH2D2A	HGNC:10821 (HGNC) 9047 (Entrez Gene) 604514 (OMIM) SH2D2A (Alliance of Genome Resources)	Chr1 q23.1	Chr1:156806243-156816848 (-) GRCh38	juvenile rheumatoid arthritis multiple sclerosis	Q9NP31 (UniProt | EBI) NM_001161443 (RefSeq)
mouse	Sh2d2a	MGI:1351596 (MGI) 27371 (Entrez Gene) Gene Tree Sh2d2a (Alliance of Genome Resources)	Chr3 38.78 cM	Chr3:87754062-87763029 (+) GRCm39		ENSMUSG00000028071 (Ensembl Gene Model) ENSMUSP00000103207 (Ensembl) ENSMUST00000107581 (Ensembl)
rat	Sh2d2a	RGD:1303076 (Rat Genome Database) 310688 (Entrez Gene) Sh2d2a (Alliance of Genome Resources)	Chr2 q34			NP_997488 (RefSeq) NM_207605 (RefSeq)
zebrafish	si:ch73-109i22.2	ZDB-GENE-141211-57 (Zebrafish Model Organism Database) 570350 (Entrez Gene) si:ch73-109i22.2 (Alliance of Genome Resources)	Chr19			XP_698916 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.