Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BMP2	HGNC:1069 (HGNC) 650 (Entrez Gene) 112261 (OMIM) BMP2 (Alliance of Genome Resources)	Chr20 p12.3	Chr20:6767686-6780246 (+) GRCh38	brachydactyly type A2 hemochromatosis type 1 osteoarthritis osteoporosis otosclerosis prostate cancer tooth agenesis	P12643 (UniProt | EBI) NM_001200 (RefSeq)
mouse	Bmp2	MGI:88177 (MGI) 12156 (Entrez Gene) Gene Tree Bmp2 (Alliance of Genome Resources)	Chr2 65.21 cM	Chr2:133394079-133404805 (+) GRCm39		ENSMUSG00000027358 (Ensembl Gene Model) ENSMUSP00000028836 (Ensembl) ENSMUST00000028836 (Ensembl)
rat	Bmp2	RGD:2211 (Rat Genome Database) 29373 (Entrez Gene) Bmp2 (Alliance of Genome Resources)	Chr3 q36			P49001 (UniProt | EBI) NM_017178 (RefSeq)
zebrafish	bmp2a	ZDB-GENE-980526-388 (Zebrafish Model Organism Database) 30631 (Entrez Gene) bmp2a (Alliance of Genome Resources)	Chr17			NP_571434 (RefSeq) NM_131359 (RefSeq)
	bmp2b	ZDB-GENE-980526-474 (Zebrafish Model Organism Database) 30632 (Entrez Gene) bmp2b (Alliance of Genome Resources)	Chr20			NP_571435 (RefSeq) NM_131360 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.