Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	POU5F1	HGNC:9221 (HGNC) 5460 (Entrez Gene) 164177 (OMIM) POU5F1 (Alliance of Genome Resources)	Chr6 p21.33	Chr6:31164337-31180731 (-) GRCh38	embryonal carcinoma seminoma	Q01860 (UniProt | EBI) NM_001285986 (RefSeq)
	POU5F1B	HGNC:9223 (HGNC) 5462 (Entrez Gene) 615739 (OMIM) POU5F1B (Alliance of Genome Resources)	Chr8 q24.21	Chr8:127322183-127420066 (+) GRCh38		Q06416 (UniProt | EBI) NM_001159542 (RefSeq)
mouse	Pou5f1	MGI:101893 (MGI) 18999 (Entrez Gene) Gene Tree Pou5f1 (Alliance of Genome Resources)	Chr17 18.69 cM	Chr17:35816929-35821674 (+) GRCm39		18999 (NCBI Gene Model) P20263 (UniProt | EBI) NM_013633 (RefSeq)
rat	Pou5f1	RGD:1359491 (Rat Genome Database) 294562 (Entrez Gene) Pou5f1 (Alliance of Genome Resources)	Chr20			NP_001009178 (RefSeq) NM_001009178 (RefSeq)
zebrafish	pou5f3	ZDB-GENE-980526-485 (Zebrafish Model Organism Database) 30333 (Entrez Gene) pou5f3 (Alliance of Genome Resources)	Chr21			Q90270 (UniProt | EBI) NM_131112 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.