Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FZD4	HGNC:4042 (HGNC) 8322 (Entrez Gene) 604579 (OMIM) FZD4 (Alliance of Genome Resources)	Chr11 q14.2	Chr11:86945679-86955395 (-) GRCh38	exudative vitreoretinopathy 1	Q9ULV1 (UniProt | EBI) NM_012193 (RefSeq)
mouse	Fzd4	MGI:108520 (MGI) 14366 (Entrez Gene) Gene Tree Fzd4 (Alliance of Genome Resources)	Chr7 49.32 cM	Chr7:89053574-89062341 (+) GRCm39	exudative vitreoretinopathy Norrie disease	14366 (NCBI Gene Model) Q61088 (UniProt | EBI) NM_008055 (RefSeq)
rat	Fzd4	RGD:71017 (Rat Genome Database) 64558 (Entrez Gene) Fzd4 (Alliance of Genome Resources)	Chr1 q32			Q9QZH0 (UniProt | EBI) NM_022623 (RefSeq)
zebrafish	fzd4	ZDB-GENE-990415-217 (Zebrafish Model Organism Database) 30363 (Entrez Gene) fzd4 (Alliance of Genome Resources)	ChrUN			NP_001292398 (RefSeq) NM_001305469 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.