Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MELK	HGNC:16870 (HGNC) 9833 (Entrez Gene) 607025 (OMIM) MELK (Alliance of Genome Resources)	Chr9 p13.2	Chr9:36572862-36677683 (+) GRCh38		Q14680 (UniProt | EBI) NM_001256687 (RefSeq)
mouse	Melk	MGI:106924 (MGI) 17279 (Entrez Gene) Gene Tree Melk (Alliance of Genome Resources)	Chr4 23.46 cM	Chr4:44300876-44364301 (+) GRCm39		17279 (NCBI Gene Model) Q61846 (UniProt | EBI) NM_010790 (RefSeq)
rat	Melk	RGD:1308974 (Rat Genome Database) 362510 (Entrez Gene) Melk (Alliance of Genome Resources)	Chr5 q22			NP_001382535 (RefSeq) NM_001395606 (RefSeq)
zebrafish	melk	ZDB-GENE-990603-5 (Zebrafish Model Organism Database) 30724 (Entrez Gene) melk (Alliance of Genome Resources)	Chr1			F1QGZ6 (UniProt | EBI) NM_206888 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.