Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DNMT1	HGNC:2976 (HGNC) 1786 (Entrez Gene) 126375 (OMIM) DNMT1 (Alliance of Genome Resources)	Chr19 p13.2	Chr19:10133342-10231286 (-) GRCh38	autosomal dominant cerebellar ataxia, deafness and narcolepsy Graves' disease hereditary sensory neuropathy hereditary sensory neuropathy type 1E lung non-small cell carcinoma	P26358 (UniProt | EBI) NM_001379 (RefSeq)
mouse	Dnmt1	MGI:94912 (MGI) 13433 (Entrez Gene) Gene Tree Dnmt1 (Alliance of Genome Resources)	Chr9 7.66 cM	Chr9:20818501-20871084 (-) GRCm39		13433 (NCBI Gene Model) P13864 (UniProt | EBI) NM_001199433 (RefSeq)
rat	Dnmt1	RGD:620979 (Rat Genome Database) 84350 (Entrez Gene) Dnmt1 (Alliance of Genome Resources)	Chr8 q13			Q9Z330 (UniProt | EBI) NM_053354 (RefSeq)
zebrafish	dnmt1	ZDB-GENE-990714-15 (Zebrafish Model Organism Database) 30430 (Entrez Gene) dnmt1 (Alliance of Genome Resources)	Chr3			NP_571264 (RefSeq) NM_131189 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.