Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TBX22	HGNC:11600 (HGNC) 50945 (Entrez Gene) 300307 (OMIM) TBX22 (Alliance of Genome Resources)	ChrX q21.1	ChrX:80014753-80031774 (+) GRCh38	Abruzzo-Erickson syndrome cleft palate X-linked cleft palate with or without ankyloglossia	Q9Y458 (UniProt | EBI) NM_001303475 (RefSeq)
mouse	Tbx22	MGI:2389465 (MGI) 245572 (Entrez Gene) Gene Tree Tbx22 (Alliance of Genome Resources)	ChrX 47.59 cM	ChrX:106711570-106732584 (+) GRCm39	X-linked cleft palate with or without ankyloglossia	ENSMUSG00000031241 (Ensembl Gene Model) ENSMUSP00000128247 (Ensembl) ENSMUST00000168174 (Ensembl)
rat	Tbx22	RGD:1589764 (Rat Genome Database) 302369 (Entrez Gene) Tbx22 (Alliance of Genome Resources)	ChrX q22			NP_001100407 (RefSeq) NM_001106937 (RefSeq)
zebrafish	tbx22	ZDB-GENE-090626-2 (Zebrafish Model Organism Database) 556143 (Entrez Gene) tbx22 (Alliance of Genome Resources)	Chr14			NP_001157933 (RefSeq) NM_001164461 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.