Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPA1	HGNC:9226 (HGNC) 5464 (Entrez Gene) 179030 (OMIM) PPA1 (Alliance of Genome Resources)	Chr10 q22.1	Chr10:70202835-70233911 (-) GRCh38		Q15181 (UniProt | EBI) NM_021129 (RefSeq)
mouse	Ppa1	MGI:97831 (MGI) 67895 (Entrez Gene) Gene Tree Ppa1 (Alliance of Genome Resources)	Chr10 32.25 cM	Chr10:61484400-61509944 (+) GRCm39		67895 (NCBI Gene Model) Q9D819 (UniProt | EBI) NM_026438 (RefSeq)
rat	Ppa1	RGD:1589773 (Rat Genome Database) 294504 (Entrez Gene) Ppa1 (Alliance of Genome Resources)	Chr20 q11			NP_001094304 (RefSeq) NM_001100834 (RefSeq)
	Sar1a	RGD:1359540 (Rat Genome Database) 361842 (Entrez Gene) Sar1a (Alliance of Genome Resources)	Chr20 q11			NP_001007740 (RefSeq) NM_001007739 (RefSeq)
zebrafish	ppa1a	ZDB-GENE-040426-1695 (Zebrafish Model Organism Database) 393706 (Entrez Gene) ppa1a (Alliance of Genome Resources)	Chr12			NP_957027 (RefSeq) NM_200733 (RefSeq)
	ppa1b	ZDB-GENE-050417-375 (Zebrafish Model Organism Database) 550531 (Entrez Gene) ppa1b (Alliance of Genome Resources)	Chr13			NP_001017833 (RefSeq) NM_001017833 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.