Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MTRFR	HGNC:26784 (HGNC) 91574 (Entrez Gene) 613541 (OMIM) MTRFR (Alliance of Genome Resources)	Chr12 q24.31	Chr12:123232914-123258079 (+) GRCh38	combined oxidative phosphorylation deficiency 7 hereditary spastic paraplegia 55	Q9H3J6 (UniProt | EBI) NM_001194995 (RefSeq)
mouse	Mtrfr	MGI:1919900 (MGI) 72650 (Entrez Gene) Gene Tree Mtrfr (Alliance of Genome Resources)	Chr5 63.52 cM	Chr5:124466152-124479907 (+) GRCm39		ENSMUSG00000047635 (Ensembl Gene Model) ENSMUSP00000076594 (Ensembl) ENSMUST00000077376 (Ensembl)
rat	Mtrfr	RGD:1563482 (Rat Genome Database) 498179 (Entrez Gene) Mtrfr (Alliance of Genome Resources)	Chr12 q15			NP_001102535 (RefSeq) NM_001109065 (RefSeq)
zebrafish	mtrfr	ZDB-GENE-130109-1 (Zebrafish Model Organism Database) 100004874 (Entrez Gene) mtrfr (Alliance of Genome Resources)	Chr5			A5WUX7 (UniProt | EBI) NM_001126476 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.