Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PIEZO1	HGNC:28993 (HGNC) 9780 (Entrez Gene) 611184 (OMIM) PIEZO1 (Alliance of Genome Resources)	Chr16 q24.3	Chr16:88715338-88785220 (-) GRCh38	dehydrated hereditary stomatocytosis 1 hereditary lymphedema	Q92508 (UniProt | EBI) NM_001142864 (RefSeq)
mouse	Piezo1	MGI:3603204 (MGI) 234839 (Entrez Gene) Gene Tree Piezo1 (Alliance of Genome Resources)	Chr8 71.31 cM	Chr8:123208437-123278068 (-) GRCm39		234839 (NCBI Gene Model) E2JF22 (UniProt | EBI) NM_001357349 (RefSeq)
rat	Piezo1	RGD:1308822 (Rat Genome Database) 361430 (Entrez Gene) Piezo1 (Alliance of Genome Resources)	Chr19 q12			Q0KL00 (UniProt | EBI) NM_001077200 (RefSeq)
zebrafish	piezo1	ZDB-GENE-041111-255 (Zebrafish Model Organism Database) 567949 (Entrez Gene) piezo1 (Alliance of Genome Resources)	Chr7			XP_696355 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.