Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MMP3	HGNC:7173 (HGNC) 4314 (Entrez Gene) 185250 (OMIM) MMP3 (Alliance of Genome Resources)	Chr11 q22.2	Chr11:102835801-102843609 (-) GRCh38	arteriosclerosis atrial fibrillation breast cancer carotid stenosis coronary artery disease end stage renal disease esophagus adenocarcinoma myocardial infarction osteoarthritis renal cell carcinoma systemic scleroderma thrombosis von Hippel-Lindau disease	P08254 (UniProt | EBI) NM_002422 (RefSeq)
mouse	Mmp3	MGI:97010 (MGI) 17392 (Entrez Gene) Gene Tree Mmp3 (Alliance of Genome Resources)	Chr9 2.46 cM	Chr9:7445845-7455975 (+) GRCm39		17392 (NCBI Gene Model) P28862 (UniProt | EBI) NM_010809 (RefSeq)
rat	Mmp3	RGD:621317 (Rat Genome Database) 171045 (Entrez Gene) Mmp3 (Alliance of Genome Resources)	Chr8 q11			P03957 (UniProt | EBI) NM_133523 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.