Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IGFBP2	HGNC:5471 (HGNC) 3485 (Entrez Gene) 146731 (OMIM) IGFBP2 (Alliance of Genome Resources)	Chr2 q35	Chr2:216632828-216664436 (+) GRCh38	obesity	P18065 (UniProt | EBI) NM_001313992 (RefSeq)
mouse	Igfbp2	MGI:96437 (MGI) 16008 (Entrez Gene) Gene Tree Igfbp2 (Alliance of Genome Resources)	Chr1 36.94 cM	Chr1:72863662-72891633 (+) GRCm39		ENSMUSG00000039323 (Ensembl Gene Model) ENSMUSP00000046610 (Ensembl) ENSMUST00000047328 (Ensembl)
rat	Igfbp2	RGD:2873 (Rat Genome Database) 25662 (Entrez Gene) Igfbp2 (Alliance of Genome Resources)	Chr9 q33			P12843 (UniProt | EBI) NM_013122 (RefSeq)
zebrafish	igfbp2a	ZDB-GENE-000125-12 (Zebrafish Model Organism Database) 794176 (Entrez Gene) igfbp2a (Alliance of Genome Resources)	Chr6			Q9PTH3 (UniProt | EBI) NM_131458 (RefSeq)
	igfbp2b	ZDB-GENE-090107-3 (Zebrafish Model Organism Database) 798920 (Entrez Gene) igfbp2b (Alliance of Genome Resources)	Chr9			B3F211 (UniProt | EBI) NM_001126464 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.