Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	VDR	HGNC:12679 (HGNC) 7421 (Entrez Gene) 601769 (OMIM) VDR (Alliance of Genome Resources)	Chr12 q13.11	Chr12:47841537-47943048 (-) GRCh38	alopecia amyotrophic lateral sclerosis aortic valve stenosis asthma atopic dermatitis autism spectrum disorder autoimmune hepatitis Barrett's esophagus basal cell carcinoma Behcet's disease breast cancer bronchopulmonary dysplasia coronary artery disease diabetic retinopathy erythema nodosum esophagus adenocarcinoma Fabry disease Graves' disease hepatitis B hepatocellular carcinoma human immunodeficiency virus infectious disease liver cirrhosis melanoma multiple sclerosis myopia otosclerosis Parkinson's disease peptic esophagitis pigmentation disease pneumonia polycystic ovary syndrome primary biliary cholangitis primary hyperparathyroidism prostate cancer psoriasis pulmonary tuberculosis rheumatoid arthritis rickets skin melanoma squamous cell carcinoma steatotic liver disease tuberculosis Turner syndrome vitamin D-dependent rickets type 2A vitiligo	P11473 (UniProt | EBI) NM_001017535 (RefSeq)
mouse	Vdr	MGI:103076 (MGI) 22337 (Entrez Gene) Gene Tree Vdr (Alliance of Genome Resources)	Chr15 53.85 cM	Chr15:97752308-97806177 (-) GRCm39	osteoporosis rickets	22337 (NCBI Gene Model) P48281 (UniProt | EBI) NM_009504 (RefSeq)
rat	Vdr	RGD:3959 (Rat Genome Database) 24873 (Entrez Gene) Vdr (Alliance of Genome Resources)	Chr7 q36			P13053 (UniProt | EBI) NM_017058 (RefSeq)
zebrafish	vdra	ZDB-GENE-000210-31 (Zebrafish Model Organism Database) 30076 (Entrez Gene) vdra (Alliance of Genome Resources)	Chr23			Q9PTN2 (UniProt | EBI) NM_130919 (RefSeq)
	vdrb	ZDB-GENE-080403-10 (Zebrafish Model Organism Database) 564511 (Entrez Gene) vdrb (Alliance of Genome Resources)	Chr6			Q1L673 (UniProt | EBI) NM_001159985 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.