Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FZD8	HGNC:4046 (HGNC) 8325 (Entrez Gene) 606146 (OMIM) FZD8 (Alliance of Genome Resources)	Chr10 p11.21	Chr10:35638247-35642296 (-) GRCh38		Q9H461 (UniProt | EBI) NM_031866 (RefSeq)
mouse	Fzd8	MGI:108460 (MGI) 14370 (Entrez Gene) Gene Tree Fzd8 (Alliance of Genome Resources)	Chr18 4.91 cM	Chr18:9212856-9216201 (+) GRCm39		14370 (NCBI Gene Model) Q61091 (UniProt | EBI) NM_008058 (RefSeq)
rat	Fzd8	RGD:1560525 (Rat Genome Database) 364754 (Entrez Gene) Fzd8 (Alliance of Genome Resources)	Chr17 q12.1			Q498S8 (UniProt | EBI) NM_001044251 (RefSeq)
zebrafish	fzd8a	ZDB-GENE-000328-3 (Zebrafish Model Organism Database) 58073 (Entrez Gene) fzd8a (Alliance of Genome Resources)	Chr24			NP_570993 (RefSeq) NM_130918 (RefSeq)
	fzd8b	ZDB-GENE-000328-4 (Zebrafish Model Organism Database) 58072 (Entrez Gene) fzd8b (Alliance of Genome Resources)	Chr2			NP_571628 (RefSeq) NM_131553 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.