Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACTB	HGNC:132 (HGNC) 60 (Entrez Gene) 102630 (OMIM) ACTB (Alliance of Genome Resources)	Chr7 p22.1	Chr7:5526409-5563902 (-) GRCh38	Baraitser-Winter syndrome 1 thrombocytopenia	P60709 (UniProt | EBI) NM_001101 (RefSeq)
mouse	Actb	MGI:87904 (MGI) 11461 (Entrez Gene) Gene Tree Actb (Alliance of Genome Resources)	Chr5 81.8 cM	Chr5:142888870-142892509 (-) GRCm39		11461 (NCBI Gene Model) P60710 (UniProt | EBI) NM_007393 (RefSeq)
rat	Actb	RGD:628837 (Rat Genome Database) 81822 (Entrez Gene) Actb (Alliance of Genome Resources)	Chr12 p11			P60711 (UniProt | EBI) NM_031144 (RefSeq)
zebrafish	actb1	ZDB-GENE-000329-1 (Zebrafish Model Organism Database) 57934 (Entrez Gene) actb1 (Alliance of Genome Resources)	Chr1			Q7ZVI7 (UniProt | EBI) NM_131031 (RefSeq)
	actb2	ZDB-GENE-000329-3 (Zebrafish Model Organism Database) 57935 (Entrez Gene) actb2 (Alliance of Genome Resources)	Chr3			Q7ZVF9 (UniProt | EBI) NM_181601 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.