Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MBL2	HGNC:6922 (HGNC) 4153 (Entrez Gene) 154545 (OMIM) MBL2 (Alliance of Genome Resources)	Chr10 q21.1	Chr10:52765380-52772784 (-) GRCh38	adult respiratory distress syndrome allergic bronchopulmonary aspergillosis aortic valve insufficiency asthma atopic dermatitis autoimmune thyroiditis bacterial infectious disease bacterial pneumonia bacterial vaginosis Behcet's disease bipolar disorder bronchiolitis obliterans bronchopulmonary dysplasia chorioamnionitis chronic obstructive pulmonary disease common variable immunodeficiency coronary restenosis Coronavirus infectious disease Crohn's disease Cryptococcal meningitis cryptosporidiosis cystic fibrosis dermatomyositis disease by infectious agent end stage renal disease fungal infectious disease hemolytic-uremic syndrome hepatitis B hepatitis C hepatocellular carcinoma herpes simplex human immunodeficiency virus infectious disease invasive aspergillosis Kartagener syndrome Kawasaki disease lepromatous leprosy liver cirrhosis liver disease lung cancer lupus nephritis obesity otitis media ovarian cancer panic disorder peripheral vascular disease Plasmodium falciparum malaria polymyalgia rheumatica psoriasis pulmonary fibrosis pulmonary tuberculosis respiratory allergy respiratory failure rhinitis sensorineural hearing loss systemic lupus erythematosus temporal arteritis thrombocytopenia toxic shock syndrome visceral leishmaniasis vitiligo vulvovaginal candidiasis	P11226 (UniProt | EBI) NM_001378374 (RefSeq)
mouse	Mbl2	MGI:96924 (MGI) 17195 (Entrez Gene) Gene Tree Mbl2 (Alliance of Genome Resources)	Chr19 25.14 cM	Chr19:30210342-30217087 (+) GRCm39		ENSMUSG00000024863 (Ensembl Gene Model) ENSMUSP00000025797 (Ensembl) ENSMUST00000025797 (Ensembl)
rat	Mbl2	RGD:67380 (Rat Genome Database) 64668 (Entrez Gene) Mbl2 (Alliance of Genome Resources)	Chr1 q52			P08661 (UniProt | EBI) NM_022704 (RefSeq)
zebrafish	hbl1	ZDB-GENE-070912-285 (Zebrafish Model Organism Database) 100007982 (Entrez Gene) hbl1 (Alliance of Genome Resources)	Chr2			XP_001341915 (RefSeq)
	hbl2	ZDB-GENE-070912-286 (Zebrafish Model Organism Database) 566971 (Entrez Gene) hbl2 (Alliance of Genome Resources)	Chr2			XP_021323412 (RefSeq)
	hbl4	ZDB-GENE-070912-287 (Zebrafish Model Organism Database) 100137128 (Entrez Gene) hbl4 (Alliance of Genome Resources)	Chr2			NP_001108197 (RefSeq) NM_001114725 (RefSeq)
	mbl2	ZDB-GENE-000427-2 (Zebrafish Model Organism Database) 100008009 (Entrez Gene) mbl2 (Alliance of Genome Resources)	Chr2			NP_571645 (RefSeq) NM_131570 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.