Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RUNX3	HGNC:10473 (HGNC) 864 (Entrez Gene) 600210 (OMIM) RUNX3 (Alliance of Genome Resources)	Chr1 p36.11	Chr1:24899511-24965138 (-) GRCh38	breast cancer developmental disorder of mental health endometrial carcinoma in situ carcinoma invasive ductal carcinoma lung non-small cell carcinoma ovarian cancer pancreatic cancer urinary bladder cancer	Q13761 (UniProt | EBI) NM_004350 (RefSeq)
mouse	Runx3	MGI:102672 (MGI) 12399 (Entrez Gene) Gene Tree Runx3 (Alliance of Genome Resources)	Chr4 67.19 cM	Chr4:134847963-134905301 (+) GRCm39	asthma idiopathic scoliosis inflammatory bowel disease	ENSMUSG00000070691 (Ensembl Gene Model) ENSMUSP00000050353 (Ensembl) ENSMUST00000056977 (Ensembl)
rat	Runx3	RGD:620082 (Rat Genome Database) 156726 (Entrez Gene) Runx3 (Alliance of Genome Resources)	Chr5 q36			NP_569109 (RefSeq) NM_001411778 (RefSeq)
zebrafish	runx3	ZDB-GENE-000605-2 (Zebrafish Model Organism Database) 58127 (Entrez Gene) runx3 (Alliance of Genome Resources)	Chr13			NP_001349273 (RefSeq) NM_131604 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.