Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KRT1	HGNC:6412 (HGNC) 3848 (Entrez Gene) 139350 (OMIM) KRT1 (Alliance of Genome Resources)	Chr12 q13.13	Chr12:52674736-52680407 (-) GRCh38	epidermolytic hyperkeratosis epidermolytic hyperkeratosis 1 epidermolytic palmoplantar keratoderma 2 keratosis palmoplantaris striata 3 KRT1-related nonepidermolytic palmoplantar keratoderma	P04264 (UniProt | EBI) NM_006121 (RefSeq)
mouse	Krt1	MGI:96698 (MGI) 16678 (Entrez Gene) Gene Tree Krt1 (Alliance of Genome Resources)	Chr15 57.06 cM	Chr15:101753861-101759221 (-) GRCm39	epidermolytic hyperkeratosis	16678 (NCBI Gene Model) P04104 (UniProt | EBI) NM_008473 (RefSeq)
rat	Krt1	RGD:1359664 (Rat Genome Database) 300250 (Entrez Gene) Krt1 (Alliance of Genome Resources)	Chr7 q36			Q6IMF3 (UniProt | EBI) NM_001008802 (RefSeq)
zebrafish	krt4	ZDB-GENE-000607-83 (Zebrafish Model Organism Database) 794486 (Entrez Gene) krt4 (Alliance of Genome Resources)	Chr6			NP_571584 (RefSeq) NM_131509 (RefSeq)
	krt5	ZDB-GENE-991110-23 (Zebrafish Model Organism Database) 797351 (Entrez Gene) krt5 (Alliance of Genome Resources)	Chr23			NP_571231 (RefSeq) NM_131156 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.