Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRPH2	HGNC:9942 (HGNC) 5961 (Entrez Gene) 179605 (OMIM) PRPH2 (Alliance of Genome Resources)	Chr6 p21.1	Chr6:42696598-42722597 (-) GRCh38	choroidal sclerosis fundus albipunctatus Leber congenital amaurosis macular degeneration patterned macular dystrophy patterned macular dystrophy 1 retinal degeneration retinitis pigmentosa retinitis pigmentosa 7 vitelliform macular dystrophy	P23942 (UniProt | EBI) NM_000322 (RefSeq)
mouse	Prph2	MGI:102791 (MGI) 19133 (Entrez Gene) Gene Tree Prph2 (Alliance of Genome Resources)	Chr17 22.91 cM	Chr17:47221404-47235859 (+) GRCm39	partial central choroid dystrophy patterned macular dystrophy 1 retinitis pigmentosa 7	19133 (NCBI Gene Model) P15499 (UniProt | EBI) NM_008938 (RefSeq)
rat	Prph2	RGD:3549 (Rat Genome Database) 25534 (Entrez Gene) Prph2 (Alliance of Genome Resources)	Chr9 q12			P17438 (UniProt | EBI) NM_013021 (RefSeq)
zebrafish	prph2a	ZDB-GENE-000616-8 (Zebrafish Model Organism Database) 58085 (Entrez Gene) prph2a (Alliance of Genome Resources)	Chr12			NP_571641 (RefSeq) NM_131566 (RefSeq)
	prph2b	ZDB-GENE-000616-9 (Zebrafish Model Organism Database) 559209 (Entrez Gene) prph2b (Alliance of Genome Resources)	Chr13			NP_571642 (RefSeq) NM_131567 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.