Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ZIC2	HGNC:12873 (HGNC) 7546 (Entrez Gene) 603073 (OMIM) ZIC2 (Alliance of Genome Resources)	Chr13 q32.3	Chr13:99981784-99986765 (+) GRCh38	holoprosencephaly holoprosencephaly 5	O95409 (UniProt | EBI) NM_007129 (RefSeq)
mouse	Zic2	MGI:106679 (MGI) 22772 (Entrez Gene) Gene Tree Zic2 (Alliance of Genome Resources)	Chr14 65.97 cM	Chr14:122712847-122717264 (+) GRCm39	holoprosencephaly 5 schizophrenia	ENSMUSG00000061524 (Ensembl Gene Model) ENSMUSP00000075283 (Ensembl) ENSMUST00000075888 (Ensembl)
rat	Zic2	RGD:1311174 (Rat Genome Database) 361096 (Entrez Gene) Zic2 (Alliance of Genome Resources)	Chr15 q25			NP_001101862 (RefSeq) NM_001108392 (RefSeq)
zebrafish	zic2a	ZDB-GENE-000710-4 (Zebrafish Model Organism Database) 58077 (Entrez Gene) zic2a (Alliance of Genome Resources)	Chr9			NP_571633 (RefSeq) NM_131558 (RefSeq)
	zic2b	ZDB-GENE-030219-92 (Zebrafish Model Organism Database) 570746 (Entrez Gene) zic2b (Alliance of Genome Resources)	Chr1			NP_001001820 (RefSeq) NM_001001820 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.