Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EDN1	HGNC:3176 (HGNC) 1906 (Entrez Gene) 131240 (OMIM) EDN1 (Alliance of Genome Resources)	Chr6 p24.1	Chr6:12230516-12297194 (+) GRCh38	aortic atherosclerosis asthma bronchiolitis obliterans chronic obstructive pulmonary disease congestive heart failure coronary artery disease coronary stenosis diabetic retinopathy hypertension obesity obstructive sleep apnea optic nerve disease rheumatoid arthritis	P05305 (UniProt | EBI) NM_001955 (RefSeq)
mouse	Edn1	MGI:95283 (MGI) 13614 (Entrez Gene) Gene Tree Edn1 (Alliance of Genome Resources)	Chr13 20.82 cM	Chr13:42454952-42461466 (+) GRCm39		13614 (NCBI Gene Model) P22387 (UniProt | EBI) NM_010104 (RefSeq)
rat	Edn1	RGD:2532 (Rat Genome Database) 24323 (Entrez Gene) Edn1 (Alliance of Genome Resources)	Chr17 p12			P22388 (UniProt | EBI) NM_012548 (RefSeq)
zebrafish	edn1	ZDB-GENE-000920-1 (Zebrafish Model Organism Database) 58032 (Entrez Gene) edn1 (Alliance of Genome Resources)	Chr19			NP_571594 (RefSeq) NM_131519 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.