Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ATP1B1	HGNC:804 (HGNC) 481 (Entrez Gene) 182330 (OMIM) ATP1B1 (Alliance of Genome Resources)	Chr1 q24.2	Chr1:169105697-169310992 (+) GRCh38	essential hypertension	P05026 (UniProt | EBI) NM_001001787 (RefSeq)
mouse	Atp1b1	MGI:88108 (MGI) 11931 (Entrez Gene) Gene Tree Atp1b1 (Alliance of Genome Resources)	Chr1 71.75 cM	Chr1:164264678-164285924 (-) GRCm39		ENSMUSG00000026576 (Ensembl Gene Model) ENSMUSP00000027863 (Ensembl) ENSMUST00000027863 (Ensembl)
rat	Atp1b1	RGD:2170 (Rat Genome Database) 25650 (Entrez Gene) Atp1b1 (Alliance of Genome Resources)	Chr13 q23			P07340 (UniProt | EBI) NM_013113 (RefSeq)
zebrafish	atp1b1a	ZDB-GENE-001127-3 (Zebrafish Model Organism Database) 64267 (Entrez Gene) atp1b1a (Alliance of Genome Resources)	Chr6			NP_571743 (RefSeq) NM_131668 (RefSeq)
	atp1b1b	ZDB-GENE-001127-4 (Zebrafish Model Organism Database) 64273 (Entrez Gene) atp1b1b (Alliance of Genome Resources)	Chr1			NP_571746 (RefSeq) NM_131671 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.