Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NRF1	HGNC:7996 (HGNC) 4899 (Entrez Gene) 600879 (OMIM) NRF1 (Alliance of Genome Resources)	Chr7 q32.2	Chr7:129611720-129757082 (+) GRCh38	Huntington's disease	Q16656 (UniProt | EBI) NM_001293163 (RefSeq)
mouse	Nrf1	MGI:1332235 (MGI) 18181 (Entrez Gene) Gene Tree Nrf1 (Alliance of Genome Resources)	Chr6 12.47 cM	Chr6:30047987-30153457 (+) GRCm39		ENSMUSG00000058440 (Ensembl Gene Model) ENSMUSP00000110860 (Ensembl) ENSMUST00000115206 (Ensembl)
rat	Nrf1	RGD:1304603 (Rat Genome Database) 312195 (Entrez Gene) Nrf1 (Alliance of Genome Resources)	Chr4 q22			Q62792 (UniProt | EBI) NM_001100708 (RefSeq)
zebrafish	nrf1	ZDB-GENE-001221-1 (Zebrafish Model Organism Database) 64604 (Entrez Gene) nrf1 (Alliance of Genome Resources)	Chr4			Q90X44 (UniProt | EBI) NM_131680 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.