Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	OPRM1	HGNC:8156 (HGNC) 4988 (Entrez Gene) 600018 (OMIM) OPRM1 (Alliance of Genome Resources)	Chr6 q25.2	Chr6:154010496-154246867 (+) GRCh38	alcohol dependence alcohol use disorder drug dependence drug psychosis heroin dependence neonatal abstinence syndrome nicotine dependence obesity opiate dependence opioid abuse post-traumatic stress disorder rheumatoid arthritis schizophrenia withdrawal disorder	P35372 (UniProt | EBI) NM_001145279 (RefSeq)
mouse	Oprm1	MGI:97441 (MGI) 18390 (Entrez Gene) Gene Tree Oprm1 (Alliance of Genome Resources)	Chr10 1.85 cM	Chr10:6708593-6988209 (+) GRCm39	autism spectrum disorder	18390 (NCBI Gene Model) P42866 (UniProt | EBI) NM_001304955 (RefSeq)
rat	Oprm1	RGD:3234 (Rat Genome Database) 25601 (Entrez Gene) Oprm1 (Alliance of Genome Resources)	Chr1 q11			P33535 (UniProt | EBI) NM_001038601 (RefSeq)
zebrafish	oprm1	ZDB-GENE-010125-1 (Zebrafish Model Organism Database) 65088 (Entrez Gene) oprm1 (Alliance of Genome Resources)	Chr13			NP_571782 (RefSeq) NM_131707 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.