Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MPZ	HGNC:7225 (HGNC) 4359 (Entrez Gene) 159440 (OMIM) MPZ (Alliance of Genome Resources)	Chr1 q23.3	Chr1:161303600-161309968 (-) GRCh38	Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease dominant intermediate D Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 2I Charcot-Marie-Tooth disease type 2J Charcot-Marie-Tooth disease type 3	P25189 (UniProt | EBI) NM_001315491 (RefSeq)
mouse	Mpz	MGI:103177 (MGI) 17528 (Entrez Gene) Gene Tree Mpz (Alliance of Genome Resources)	Chr1 79.05 cM	Chr1:170978282-170988699 (+) GRCm39	Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 3 neuropathy PCWH syndrome	17528 (NCBI Gene Model) P27573 (UniProt | EBI) NM_008623 (RefSeq)
rat	Mpz	RGD:3109 (Rat Genome Database) 24564 (Entrez Gene) Mpz (Alliance of Genome Resources)	Chr13 q24			P06907 (UniProt | EBI) NM_017027 (RefSeq)
zebrafish	mpz	ZDB-GENE-010724-4 (Zebrafish Model Organism Database) 114417 (Entrez Gene) mpz (Alliance of Genome Resources)	Chr2			NP_919342 (RefSeq) NM_194361 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.