Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ANGPT1	HGNC:484 (HGNC) 284 (Entrez Gene) 601667 (OMIM) ANGPT1 (Alliance of Genome Resources)	Chr8 q23.1	Chr8:107249482-107498055 (-) GRCh38	alcohol dependence brain ischemia diabetic retinopathy hereditary angioedema hypertension	Q15389 (UniProt | EBI) NM_139290 (RefSeq)
mouse	Angpt1	MGI:108448 (MGI) 11600 (Entrez Gene) Gene Tree Angpt1 (Alliance of Genome Resources)	Chr15 16.69 cM	Chr15:42288119-42540373 (-) GRCm39		ENSMUSG00000022309 (Ensembl Gene Model) ENSMUSP00000022921 (Ensembl) ENSMUST00000022921 (Ensembl)
rat	Angpt1	RGD:628896 (Rat Genome Database) 89807 (Entrez Gene) Angpt1 (Alliance of Genome Resources)	Chr7 q31			O35460 (UniProt | EBI) NM_053546 (RefSeq)
zebrafish	angpt1	ZDB-GENE-010817-1 (Zebrafish Model Organism Database) 114407 (Entrez Gene) angpt1 (Alliance of Genome Resources)	Chr19			NP_571888 (RefSeq) NM_131813 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.