Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP1A1	HGNC:2595 (HGNC) 1543 (Entrez Gene) 108330 (OMIM) CYP1A1 (Alliance of Genome Resources)	Chr15 q24.1	Chr15:74719542-74725536 (-) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia ankylosing spondylitis Behcet's disease biliary tract cancer breast cancer bronchitis chronic myeloid leukemia chronic obstructive pulmonary disease clubfoot cystic fibrosis diabetes mellitus endometrial cancer end stage renal disease esophageal cancer esophagus squamous cell carcinoma gallbladder cancer Graves' disease head and neck cancer hypospadias lung cancer multiple myeloma oral cavity cancer oral squamous cell carcinoma Parkinson's disease periodontitis pneumonia polycystic ovary syndrome porphyria cutanea tarda prostate cancer psoriasis psoriatic arthritis reactive arthritis renal cell carcinoma Sjogren's syndrome stomach cancer systemic lupus erythematosus type 2 diabetes mellitus urinary bladder cancer	P04798 (UniProt | EBI) NM_000499 (RefSeq)
mouse	Cyp1a1	MGI:88588 (MGI) 13076 (Entrez Gene) Gene Tree Cyp1a1 (Alliance of Genome Resources)	Chr9 31.34 cM	Chr9:57595211-57611107 (+) GRCm39		13076 (NCBI Gene Model) P00184 (UniProt | EBI) NM_009992 (RefSeq)
rat	Cyp1a1	RGD:2458 (Rat Genome Database) 24296 (Entrez Gene) Cyp1a1 (Alliance of Genome Resources)	Chr8 q24			P00185 (UniProt | EBI) NM_012540 (RefSeq)
zebrafish	cyp1a	ZDB-GENE-011219-1 (Zebrafish Model Organism Database) 140634 (Entrez Gene) cyp1a (Alliance of Genome Resources)	Chr18			NP_571954 (RefSeq) NM_131879 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.