Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HNF1B	HGNC:11630 (HGNC) 6928 (Entrez Gene) 189907 (OMIM) HNF1B (Alliance of Genome Resources)	Chr17 q12	Chr17:37686431-37745059 (-) GRCh38	kidney disease maturity-onset diabetes of the young type 5 pancreas disease renal cell carcinoma type 2 diabetes mellitus	P35680 (UniProt | EBI) NM_001165923 (RefSeq)
mouse	Hnf1b	MGI:98505 (MGI) 21410 (Entrez Gene) Gene Tree Hnf1b (Alliance of Genome Resources)	Chr11 51.23 cM	Chr11:83741035-83796743 (+) GRCm39		21410 (NCBI Gene Model) P27889 (UniProt | EBI) NM_009330 (RefSeq)
rat	Hnf1b	RGD:3830 (Rat Genome Database) 25640 (Entrez Gene) Hnf1b (Alliance of Genome Resources)	Chr10 q26			P23899 (UniProt | EBI) NM_001308149 (RefSeq)
zebrafish	hnf1ba	ZDB-GENE-020104-1 (Zebrafish Model Organism Database) 792391 (Entrez Gene) hnf1ba (Alliance of Genome Resources)	Chr15			A1L1N5 (UniProt | EBI) NM_131880 (RefSeq)
	hnf1bb	ZDB-GENE-030131-3003 (Zebrafish Model Organism Database) 324283 (Entrez Gene) hnf1bb (Alliance of Genome Resources)	Chr21			Q8UW00 (UniProt | EBI) NM_194372 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.