Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTK2	HGNC:9611 (HGNC) 5747 (Entrez Gene) 600758 (OMIM) PTK2 (Alliance of Genome Resources)	Chr8 q24.3	Chr8:140657900-141002216 (-) GRCh38	leiomyoma lung small cell carcinoma pulmonary hypertension	Q05397 (UniProt | EBI) NM_001352746 (RefSeq)
mouse	Ptk2	MGI:95481 (MGI) 14083 (Entrez Gene) Gene Tree Ptk2 (Alliance of Genome Resources)	Chr15 33.94 cM	Chr15:73076951-73295129 (-) GRCm39		ENSMUSG00000022607 (Ensembl Gene Model) ENSMUSP00000159174 (Ensembl) ENSMUST00000239146 (Ensembl)
rat	Ptk2	RGD:3443 (Rat Genome Database) 25614 (Entrez Gene) Ptk2 (Alliance of Genome Resources)	Chr7 q34			O35346 (UniProt | EBI) NM_013081 (RefSeq)
zebrafish	ptk2aa	ZDB-GENE-031114-5 (Zebrafish Model Organism Database) 386705 (Entrez Gene) ptk2aa (Alliance of Genome Resources)	Chr19			NP_942114 (RefSeq) NM_198819 (RefSeq)
	ptk2ab	ZDB-GENE-020114-1 (Zebrafish Model Organism Database) 142986 (Entrez Gene) ptk2ab (Alliance of Genome Resources)	Chr16			NP_571871 (RefSeq) NM_131796 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.